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Rapidly obtain sections as skinny or thick as your software involves, without worrying about shedding or distorting precious tissue samples.

Megatome is actually a vibrating microtome intended to part a wide selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows high-throughput tissue sectioning with uniform area profile, along with nominal tissue problems and knowledge decline.

Antibodies may perhaps choose months to diffuse as a result of only some millimeters of tissue, which has a steep labeling gradient from area to Main.

Megatome is suitable for precision: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and contains a exclusive deflection Management system.

SE uses a rotational electrical subject to disperse hugely electromobile molecules (for example antibodies or surfactant micelles) during a porous sample with out damaging electrically billed buildings in the tissue. This permits 2-4 working day clearing of intact organs,

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Megatome is usually a novel microtome that enables for high-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue problems and information decline.

eFLASH can be a rapid tissue labeling procedure that permits for uniform full-organ staining in 20 rounds of labeling.

The SmartSPIM gentle sheet microscope gives unparalleled resolution and acquisition velocity during intact tissue volumes, while its modular layout allows you to up grade and customize specific components.

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Possibly download a release or develop a distribution zip as outlined higher than. Unzip the archive to some sought after locale.

Leverage the Clear+ tissue clearing approach, in conjunction with eFLASH and patented stochastic electrotransport systems, to rapidly very clear and label complete organs. Critical highlights and options consist of:

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